| 06/2009 |
Synthesis and optimization of 2-pyridin-3-yl-benzo[d][1,3]oxazin-4-one based inhibitors of human neutrophil elastase |
| 03/2009 |
Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH) |
| 02/2009 |
The Biochemistry of Disease: Desperately Seeking Syzygy |
| 08/2008 |
Design and synthesis of AX4697, a bisindolylmaleimide exo-affinity probe that labels protein kinase C alpha and beta |
| 05/2008 |
Discovery of AX8312, an N-alkyl-Gly-boro-Pro Derivative that Accelerates Recovery from Neutropenia in the Mouse |
| 08/2007 |
Novel Mechanistic Class of Fatty Acid Amide Hydrolase Inhibitors with Remarkable Selectivity |
| 01/2007 |
Polo-like kinases inhibited by wortmannin. Labeling site and downstream effects |
| 01/2007 |
Synthesis and activity of a potent, specific
azabicyclo[3.3.0]-octane-based DPP II inhibitor |
| 01/2007 |
Functional Interrogation of the Kinome using Nucleotide Acyl Phosphates |
| 10/2005 |
Boro-norleucine as a P1 residue for the design of selective and potent DPP7 inhibitorsent DPP7 inhibitors |
| 10/2005 |
Synthesis and structure-activity relationship of N-alkyl Gly-boro-Pro inhibitors of DPP4, FAP, and DPP7 |
| 04/2005 |
Evaluation of Clinical Colon Carcinoma Using Activity-Based Proteomic Profiling |
| 02/2005 |
High-resolution functional proteomics by active-site peptide profiling |
| 01/2005 |
Wortmannin, a Widely Used Phosphoinositide 3-Kinase Inhibitor, also Potently Inhibits Mammalian Polo-like Kinase |
| 07/2004 |
Synthesis of AX7593, a Quinazoline-Derived Photoaffinity Probe for EGFR |
| 07/2004 |
The Development and Application of Methods for Activity-based Protein Profiling |
| 05/2004 |
Design and Synthesis of AX7574: A Microcystin-Derived, Fluorescent Probe for Serine/Threonine Phosphatases |
| 03/2004 |
Synergistic Computational and Experimental Proteomics Approaches for More Accurate Detection of Active Serine Hydrolases in Yeast |
| 01/2004 |
Mapping Enzyme Active Sites in Complex Proteomes |
| 01/2004 |
Chemical Strategies for Activity-Based Proteomics |
| 08/2003 |
Prolyl peptidases: a serine protease subfamily with high potential for drug discovery |
| 04/2003 |
Functional profiling of the proteome with affinity labels |
| 04/2003 |
Proteomic Tools for Quantitation by Mass Spectrometry |
| 06/2003 |
Discovering Potent and Selective Reversible Inhibitors of Enzymes in Complex Proteomes |
| 02/2003 |
Activity-Based Protein Profiling in Vivo Using a Copper(I)-Catalyzed Azide-Alkyne [3+2] Cycloaddition |
| 02/2003 |
Inhibitor Focusing: Direct Selection of Drug Targets from Proteomes Using Activity-Based Probes |
| 02/2003 |
Activity-based proteomics: enzyme chemistry redux |
| 09/2002 |
Trifunctional chemical probes for the consolidated detection and identification of enzyme activities from complex proteomes |
| 10/2002 |
Chemical strategies for functional proteomics |
| 08/2002 |
Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness |
| 07/2002 |
Proteomic profiling of mechanistically distinct enzyme classes using a common chemotype |
| 07/2002 |
Activity-based probes for functional proteomics |
| 09/2001 |
Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes |
| 03/2001 |
Profiling Serine Hydrolase Activities in Complex Proteomes |
| 01/2001 |
Profiling the specific reactivity of the proteome with non-directed activity-based probes |
| 02/2000 |
Chemical strategies for the global analysis of protein function |
| 12/1999 |
Activity-based protein profiling: The serine hydrolases |
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